Alexa Fluor? 488 Mouse Anti-Human CD10 Antibody (S-713-5)

產(chǎn)品型號(hào)：S0B5264

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD10, also known as neutral endopeptidase, neprilysin, or common acute lymphoblastic leukemia antigen （CALLA）, is a zinc-dependent metalloprotease found on the cell surface. It is a single-pass type II transmembrane glycoprotein with a molecular weight of around 100 kDa, belonging to the peptidase M13 family. CD10 plays a crucial role in various physiological and pathological processes, including cardiovascular regulation, immune function, fetal development, pain response, oncogenesis, and aging. It acts by cleaving and inactivating a wide range of biologically active neuropeptides, such as substance P, bradykinin, and oxytocin, thereby modulating neurotransmitter levels, blood pressure, and inflammatory responses. CD10 is also recognized as a biomarker for hematopoietic and tissue stem cells and has prognostic significance in the progression of leukemia and various solid tumors. In addition, it has been found to have therapeutic potential in diseases like Alzheimer’s disease, heart failure, obesity, and type-2 diabetes.

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