13774214275
13774214275
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產品型號：S0B5391
更新時間：2025-10-09
廠商性質：生產廠家
訪問量：114
服務熱線15855403091
Neural cell adhesion molecule 1 （NCAM-1）, also known as CD56, is a cell adhesion protein belonging to the immunoglobulin superfamily. It is expressed on various cell types including neurons, muscle cells, and immune cells like natural killer （NK） cells. NCAM-1/CD56 plays crucial roles in cell-to-cell and cell-matrix interactions during development and differentiation, regulating processes such as neurogenesis, neurite outgrowth, axonal guidance, and cell migration in the nervous system. In the immune system, it is involved in the expansion of T lymphocytes, B lymphocytes, and NK cells. NCAM-1/CD56 also triggers signaling cascades involving FYN-focal adhesion kinase （FAK）, mitogen-activated protein kinase （MAPK）, and phosphatidylinositol 3-kinase （PI3K）. Additionally, it serves as a biomarker for certain diseases, such as malignant tumors in the nervous system and neuroendocrine carcinoma.
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