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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2167Ki67 Mouse mAb (SDT-606-33)
產(chǎn)品型號：S0B2167
更新時間：2025-10-10
廠商性質：生產(chǎn)廠家
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服務熱線15855403091
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相關文章
The Ki-67 protein （also known as MKI67） is a cellular marker for proliferation, and can be used in immunohistochemistry. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle （G1, S, G2, and mitosis）, but is absent in resting （quiescent） cells （G0）. Cellular content of Ki-67 protein markedly increases during cell progression through S phase of the cell cycle. In breast cancer Ki67 identifies a high proliferative subset of patients with ER-positive breast cancer who derive greater benefit from adjuvant chemotherapy.
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